Liverpool slipped to just their second Premier League defeat of the season after former Reds striker Danny Ings earned Southampton a surprise 1-0 win at St Mary’s.
Jurgen Klopp’s side were forced to start the match without a recognised centre-back, and their makeshift backline was breached after just 111 seconds, with Ings brilliantly hooking his 50th Premier League goal over Alisson to break the deadlock.
It took Liverpool until the 75th minute to have a shot target, and even that was a tame effort from Mane, as their famed front three had a rare off day. Saints were in fact comfortable in seeing out the win.
The defeat opens the door for Manchester United, who can go top of the table outright with even just a draw from their game in hand against Burnley next week.